Professor, Department of Bioengineering and Therapeutic Sciences and Department of Pharmaceutical Chemistry at UCSF.
The Sali group is using computation grounded in the laws of physics and evolution to study the structure and function of proteins. We aim to improve and apply methods for:
- predicting the structures of proteins;
- determining the structures of macromolecular assemblies;
- annotating the functions of proteins using their structures.
This research enhances the impact of genome sequencing, structural genomics, and functional genomics on biology and medicine.